BOLETÍN BIBLIOGRÁFICO
DE INMUNOTERAPIA
Artículo destacado – Septiembre 2023
1
El futuro de la ITA en 7 preguntas.
Future directions of Allergen Immunotherapy (AIT) for allergic rhinitis: an experts' perspective.
Pfaar O, Portnoy J, Nolte H, Chaker AM, Luna-Pech JA, Patterson A, Pandya A, Larenas-Linnemann D
J Allergy Clin Immunol Pract. 2023 Sep 14:S2213-2198(23)01015-2. doi: 10.1016/j.jaip.2023.08.047. Epub ahead of print. PMID: 37716529.
BACKGROUND
Allergen Immunotherapy (AIT) is broadly used all over the world as the only available disease-modifying treatment option. The aim of this experts' perspective is to address seven important unmet needs for the further direction of AIT and to provide the readership with the authors' positions on these topics.
METHODS
An international group of experts in the field of AIT have formulated seven important aspects for the future position of AIT, performed a current literature review and proposed a consented position on these topics.
RESULTS
The aspects discussed and consented by the authors include i) alternative routes of allergen application in AIT, ii) the potential of recombinant vaccines, iii) the role of allergy diagnosis based on component-resolved diagnosis for AIT composition, iv) the impact of COVID-19 vaccination for further innovations in AIT, v) potential of combining biologics to AIT, vi) future innovations in high-risk children/adolescents and vii) the future regulatory position on AIT.
CONCLUSION
Important unmet needs and topics for AIT have been addressed in this expert review. The authors' views and personal position on these seven aspects have also been elaborated.